Exemestane
Chemical Name: 6-Methyleneandrosta-1,4-diene-3,17-dione
Purity: ≥99%
Biological Activity
Exemestane is an irreversible steroidal aromatase inhibitor (IC50 = 20 nM). Destabilizes aromatase and lowers estrogen levels; orally active.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
-
Aromatase destabilizer: novel action of exemestane, a Food and Drug Administration-approved aromatase inhibitor.
Wang and Chen
Cancer Res., 2006;66:10281 -
Aromatase inhibitors: are there differences between steroidal and nonsteroidal aromatase inhibitors and do they matter?
Miller et al.
Oncologist, 2008;13:829 -
The steroidal aromatase inhibitor exeme. prevents bone loss in ovariectomized rats.
Goss et al.
Bone, 2004;34:384
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for Exemestane
The citations listed below are publications that use Tocris products. Selected citations for Exemestane include:
1 Citation: Showing 1 - 1
-
Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain.
Authors: Adele M Et al.
Sci Adv 2022;8:eabo5633
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Exemestane
There are currently no reviews for this product. Be the first to review Exemestane and earn rewards!
Have you used Exemestane?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
