FACA/FANCA Antibody (4Q1Q8)

Novus Biologicals | Catalog # NBP3-16818

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 4Q1Q8 expressed in HEK293
View all FACA/FANCA Primary Antibodies »

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 2-104 of human FACA/FANCA (O15360). SDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASR

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for FACA/FANCA Antibody (4Q1Q8)

Western Blot: FACA/FANCA Antibody (4Q1Q8) [NBP3-16818]

Western Blot: FACA/FANCA Antibody (4Q1Q8) [NBP3-16818]

Western Blot: FACA/FANCA Antibody (4Q1Q8) [NBP3-16818] - Western blot analysis of extracts of various cell lines, using FACA/FANCA Rabbit mAb (NBP3-16818) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Applications for FACA/FANCA Antibody (4Q1Q8)

Application
Recommended Usage

Western Blot

1:500 - 1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol, 0.05% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: FACA/FANCA

FANCA (Fanconi anemia group A) protein is a DNA repair protein that may function as a cell cycle checkpoint or in postreplication repair. FANCA may also be important for the maintenance of chromosome stability and reparation of interstrand DNA cross linkages.

Defects in FANCA result in Fanconi Anemia, a genetically heterogeneous autosomal recessive disorder characterized by progressive pancytopenia, diverse congenital malformations, and a predisposition to develop malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair. At the cellular level FANCA defects cause a hypersensitivity to DNA-damaging agents, chromosomal instability, and defective DNA repair.

Long Name

Fanconi Anemia, Complementation Group A

Alternate Names

FAA, FAH, FANCA, FANCH

Gene Symbol

FANCA

Additional FACA/FANCA Products

Product Documents for FACA/FANCA Antibody (4Q1Q8)

Certificate of Analysis

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Product Specific Notices for FACA/FANCA Antibody (4Q1Q8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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