FC 131

Name: FC 131
Brand: Tocris Bioscience
SKU: 4320

Tocris Bioscience | Catalog # 4320

Submit a review

Product Documents

CXCR4 antagonist

Discontinued Product

4320 has been discontinued. View all Chemokine Receptor Antagonists products.

Technical Data
Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

CXCR4 antagonist

View all Chemokine Receptor Antagonists »

Product Description

CXCR4 antagonist (IC₅₀ = 126 nM). Displays anti-HIV activity in assays using NL4-3 and IIIB strains (EC₅₀ = 21 nM for both strains).

Product Specifications for FC 131

Molecular Weight

729.84

Formula

C₃₆H₄₇N₁₁O₆

Storage

Store at -20°C

CAS Number

606968-52-9

PubChem ID

5275848

InChI Key

MBXBICVKLVYNKD-QUAHOIDUSA-N

SMILES

NC(=N)NCCC[C@@H]1NC(=O)[C@@H](CC2=CC=C(O)C=C2)NC(=O)CNC(=O)[C@@H](CC2=CC3=CC=CC=C3C=C2)NC(=O)[C@H](CCCNC(N)=N)NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 2mg/ml in water

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product.

Inokuchi Potent CXCR4 antagonists containing amidine type peptide bond isosteres. ACS Med.Chem.Lett.
Tamamura Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131 J.Med.Chem. 2005 PMID: 15658852

Product Documents for FC 131

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for FC 131

For research use only

Customer Reviews for FC 131

There are currently no reviews for this product. Be the first to review FC 131 and earn rewards!

Have you used FC 131?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image