Recombinant Human Fc gamma RIIIB/CD16b His Protein

Name: Recombinant Human Fc gamma RIIIB/CD16b His Protein
Brand: Novus Biologicals
SKU: NBP2-61175
Price: 1599 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-61175

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

Baculovirus

Tag

His

Applications

SDS-PAGE

View all Fc gamma RIIIB/CD16b Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 21-200 of Human Fc gamma RIII (CD16)

Source: Baculovirus

Amino Acid Sequence: EDLPKAVVFL EPQWYSVLEK DSVTLKCQGA YSPEDNSTQW FHNENLISSQ ASSYFIDAAT VNDSGEYRCQ TNLSTLSDPV QLEVHIGWLL LQAPRWVFKE EDPIHLRCHS WKNTALHKVT YLQNGKDRKY FHHNSDFHIP KATLKDSGSY FCRGLVGSKN VSSETVNITI TQGLAVSTIS VEHHHHHH

Purity

>90%, by SDS-PAGE

Endotoxin Level

< 1.0 EU per 1ug of protein (determined by LAL method)

Predicted Molecular Mass

21.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Fc gamma RIIIB/CD16b His Protein

SDS-PAGE: Recombinant Human Fc gamma RIIIB/CD16b His Protein [NBP2-61175]

SDS-Page: Recombinant Human Fc gamma RIIIB/CD16b Protein [NBP2-61175] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP2-61175

Formulation	PBS (pH 7.4), 10% glycerol
Preservative	No Preservative
Concentration	0.25 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Fc gamma RIIIB/CD16b

CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.

Long Name

Fc gamma Receptor III

Alternate Names

CD16b, FCG3, FCGR3B, FcgRIIIB, FcR-10, FCRIIIB, IGFR3

Gene Symbol

FCGR3B

Additional Fc gamma RIIIB/CD16b Products

Product Documents for Recombinant Human Fc gamma RIIIB/CD16b His Protein

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Product Specific Notices for Recombinant Human Fc gamma RIIIB/CD16b His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.