Fenretinide

Tocris Bioscience | Catalog # 1396

Synthetic retinoid; antiproliferative and antioxidant
Tocris Bioscience

Key Product Details

Description

Synthetic retinoid; antiproliferative and antioxidant

Alternative Names

4-HPR
View all Additional Retinoic Acid Receptor Compounds »

Product Description

Fenretinide is a synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids.

Product Specifications for Fenretinide

Molecular Weight

391.55

Formula

C26H33NO2

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-(4-Hydroxyphenyl)retinamide

CAS Number

65646-68-6

PubChem ID

5288209

InChI Key

AKJHMTWEGVYYSE-FXILSDISSA-N

SMILES

CC(/C=C/C1=C(C)CCCC1(C)C)=C\C=C\C(C)=C\C(=O)NC1=CC=C(O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 39.16 100
Ethanol 39.16 100

Preparing Stock Solutions for Fenretinide

The following data is based on the product molecular weight 391.55.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.55 mL 12.77 mL 25.54 mL
5 mM 0.51 mL 2.55 mL 5.11 mL
10 mM 0.26 mL 1.28 mL 2.55 mL
50 mM 0.05 mL 0.26 mL 0.51 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 26 publications citing the usage of this product.

Product Documents for Fenretinide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Fenretinide

For research use only

Customer Reviews for Fenretinide (1)

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  • Fenretinide was tested to understand its induction of apoptotic cell death in B-cell non-Hodgkin lymphoma
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 12/23/2019
    Fenretinide at 900 mg/m2 PO BID for days 1–5 of a 7-day cycle used.
    Fenretinide was tested to understand its induction of apoptotic cell death in B-cell non-Hodgkin lymphoma (NHL).
    Fenretinide 1396

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