Chemical Name: α,α-Dimethyl-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-benzeneacetic acid hydrochloride
Biological ActivityFexofenadine hydrochloride is a selective histamine H1 receptor antagonist (pKi = 8.1). Active metabolite of terfenadine that displays non-sedating antiallergic effects.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Markham and Wagstaff
Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis.
Sakairi et al.
Changes in pH differently affect the binding properties of histamine H1 receptor antagonists.
Gillard and Chatelaine
Citation for Fexofenadine hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Fexofenadine hydrochloride include:
1 Citation: Showing 1 - 1
A modified grapefruit juice eliminates two compound classes as major mediators of the grapefruit juice-fexofenadine interaction: an in vitro-in vivo " connect".
Authors: Won Et al.
Mucosal Immunol 2013;53:982
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