Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Janelia Fluor 525

Antibody Source

Monoclonal Mouse IgG2B Clone # 224812
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Product Specifications

Immunogen

E. coli-derived recombinant human FGF-11
Met1-Pro225 (predicted)
Accession # Q2YDX8

Specificity

Detects human FGF-11 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with bovine FGF acidic, bovine FGF basic, recombinant human (rh) FGF acidic, rhFGF basic, rhFGF-3, -4, -5, -6, -7, -8b, -9, -10, -12, -13, -16, -17, -18, -19, -20, recombinant mouse FGF-8b, 8c, or -15 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for FGF-11 Antibody (224812) [Janelia Fluor® 525]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: FGF-11

FGF11 encodes a 225 amino acid long, 25 kDA fibroblast growth factor 11 protein that probably acts in nervous system development and function as it is a member of the fibroblast growth factor (FGF) family. Its exact function is unknown but the pattern of expression in mouse homolog implies this nervous system development. FGF11 is associated with breast cancer, melanoma, adenocarcinoma, and pancreatitis. It participates in the regulation of actin cytoskeleton, melanoma, MAPK signaling pathway, paxillian interaction, telomerase components in cell signaling, and mitochondrial apoptosis. FGF11 is known to interact with genes: EGFR, FGFR1, FGFR2, FGFR3, and FGFR4.

Long Name

Fibroblast Growth Factor 11

Alternate Names

FGF11

Gene Symbol

FGF11

Additional FGF-11 Products

Product Documents for FGF-11 Antibody (224812) [Janelia Fluor® 525]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for FGF-11 Antibody (224812) [Janelia Fluor® 525]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

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