FGL2 (fibrinogen-like protein 2), also called fibroleukin, is a 64-70 kDa secreted glycoprotein of the Fibrinogen-like superfamily. In the presence of acidic phospholipids and calcium, FGL2 has prothrombinase activity and acts as a procoagulant. In soluble form, FGL2 promotes T regulatory (Treg) activity and suppresses DC, T, and B cell immune reactivity, acting as an immune suppressor. A 260-280 aa FGL2 complex is thought to be a homotetramer.
FGL2/Fibroleukin Antibody (829321) [FITC]
Novus Biologicals | Catalog # FAB5257F
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot
Label
FITC (Excitation = 495 nm, Emission = 519 nm)
Antibody Source
Monoclonal Rat IgG2A Clone # 829321
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Product Specifications
Immunogen
Chinese Hamster Ovary cell line, CHO-derived mouse FGL2
Val20-Pro432
Accession # P12804
Val20-Pro432
Accession # P12804
Specificity
Detects mouse FGL2 in direct ELISAs.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for FGL2/Fibroleukin Antibody (829321) [FITC]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: FGL2
Long Name
Fibrinogen-like 2
Alternate Names
Fibroleukin, T49
Additional FGL2 Products
Product Documents for FGL2/Fibroleukin Antibody (829321) [FITC]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for FGL2/Fibroleukin Antibody (829321) [FITC]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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