Human Fibulin 5/DANCE ELISA Kit (Colorimetric)

Key Product Details

Product Specifications

Precision

Intra-Assay Precision (Precision within an assay) %CV 10 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) %CV 12 (example only; lot dependent)

Scientific Data Images for Human Fibulin 5/DANCE ELISA Kit (Colorimetric)

Kit Contents for Human Fibulin 5/DANCE ELISA Kit (Colorimetric)

• Detection Reagent A
• Detection Reagent B
• Diluent Buffer
• Instruction manual
• Plate sealer for 96 wells
• Pre-coated 96T strip plate
• Standard
• Stop Solution
• TMB Substrate
• Wash Buffer (30 x concentrate)

Preparation and Storage

Background: Fibulin 5/DANCE

Fibulin 5, also known as DANCE and EVEC, is a secreted matricellular glycoprotein that is expressed by smooth muscle cells and endothelial cells of the developing vasculature as well as by migrating neural crest cells and lung interstitial fibroblasts. It is downregulated in the adult vasculature but is re-expressed at aortic branching points, in the uterus, and at sites of mechanical or atherosclerotic injury. Fibulin 5 anchors cells to the extracellular matrix, promotes elastic fiber assembly and maturation, and functions as an angiogenesis inhibitor. It can function either as a tumor suppressor or enhancer of tumor cell invasiveness. Defects in Fibulin 5 expression or function can result in a loss of connective tissue integrity, cardiac elasticity, and ability to remodel the vasculature after injury.

Additional Fibulin 5/DANCE Products

• All Products for Fibulin 5/DANCE
• Fibulin 5/DANCE ELISA Kits
• Fibulin 5/DANCE Lysates
• Fibulin 5/DANCE Primary Antibodies
• Fibulin 5/DANCE Proteins and Enzymes

Product Documents for Human Fibulin 5/DANCE ELISA Kit (Colorimetric)