Flufenamic acid

Tocris Bioscience | Catalog # 4522

Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6
Tocris Bioscience

Key Product Details

Description

Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6
View all Calcium-activated Chloride Channel Blockers »

Product Description

Flufenamic acid is a nonsteroidal anti-inflammatory drug (NSAID). Inhibits calcium-activated chloride channels (CaCCs). Also increases currents through TRPC6 channels and inhibits currents through TRPC3 and TRPC7 channels.

Product Specifications for Flufenamic acid

Molecular Weight

281.23

Formula

C14H10F3NO2

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid

CAS Number

530-78-9

PubChem ID

3371

InChI Key

LPEPZBJOKDYZAD-UHFFFAOYSA-N

SMILES

O=C(C1=C(NC2=CC=CC(C(F)(F)F)=C2)C=CC=C1)O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 28.12 100
Ethanol 28.12 100

Preparing Stock Solutions for Flufenamic acid

The following data is based on the product molecular weight 281.23.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.56 mL 17.78 mL 35.56 mL
5 mM 0.71 mL 3.56 mL 7.11 mL
10 mM 0.36 mL 1.78 mL 3.56 mL
50 mM 0.07 mL 0.36 mL 0.71 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 20 publications citing the usage of this product.

Product Documents for Flufenamic acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Flufenamic acid

For research use only

Citations for Flufenamic acid

Customer Reviews for Flufenamic acid (1)

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  • Flufenamic Acid interaction with AKR1C4 protein was measured
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 08/26/2019
    Flufenamic Acid interaction with AKR1C4 protein was measured. The activity relation pattern observed.

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