Formoterol hemifumarate

Key Product Details

Product Description

Formoterol hemifumarate is a potent, selective and long-acting β₂-adrenoceptor agonist. Displays 330-fold selectivity for β₂ over β₁ receptors (pK_d values are 8.12 and 5.58 respectively). Potently relaxes guinea pig trachea (pD₂ = 9.29), and is longer-acting and 100-fold more potent than Salbutamol (Cat. No. 0634).

Product Specifications for Formoterol hemifumarate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Formoterol hemifumarate

The following data is based on the product molecular weight 402.45.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.5 mM	4.97 mL	24.85 mL	49.70 mL
2.5 mM	0.99 mL	4.97 mL	9.94 mL
5 mM	0.50 mL	2.48 mL	4.97 mL
25 mM	0.10 mL	0.50 mL	0.99 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 19 publications citing the usage of this product.

• Decker Effects of N-aralkyl substitution of β-agonists on α- and β-adrenoceptor subtypes: pharmacological studies and binding assays. J.Pharm.Pharmacol. 1982 PMID: 6121868
• Naline Relaxant effects and durations of action of formo. and salme. on the isolated human bronchus. Eur.Respir.J. 1994 PMID: 7914176
• Anderson Formoterol: pharmacology, molecular basis of agonism, and mechanism of long duration of a highly potent and selective β₂-adrenoceptor agonist bronchodilator. Life Sci. 1993 PMID: 8099696

Product Documents for Formoterol hemifumarate