Salbutamol hemisulfate

Key Product Details

Product Description

Salbutamol hemisulfate is a selective β₂-adrenergic agonist with 29-fold higher selectivity for β₂ over β₁ receptors. Salbutamol elevates fibroblast growth factor 20 (FGF20) in nigrostriatal neurons, and is neuroprotective in a mouse model of Parkinson's disease.

Product Specifications for Salbutamol hemisulfate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Salbutamol hemisulfate

The following data is based on the product molecular weight 288.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.47 mL	17.34 mL	34.68 mL
5 mM	0.69 mL	3.47 mL	6.94 mL
10 mM	0.35 mL	1.73 mL	3.47 mL
50 mM	0.07 mL	0.35 mL	0.69 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 23 publications citing the usage of this product.

• Baker The selectivity of beta-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors. Br.J.Pharmacol. 2005 PMID: 15655528
• Fletcher Targeted repositioning identifies drugs that increase fibroblast growth factor 20 production and protect against 6-hydroxydopamine-induced nigral cell loss in rats. Sci.Rep. 2019 PMID: 31171821
• Prior Effects of the enantiomers of R,S-salbutamol on incompletely fused tetanic contractions of slow- and fast-twitch skeletal muscles of the guinea-pig. Br.J.Pharmacol. 1998 PMID: 9504397
• Strosberg and Pietri-Rouxel Function and regulation of the β₃-adrenoceptor. TiPS 1996 PMID: 8979772
• January Salmeterol-induced desensitisation, internalization and phosphorylation of the human β₂-adrenoceptor. Br.J.Pharmacol. 1998 PMID: 9517390

Product Documents for Salbutamol hemisulfate