Chemical Name: 7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid
Biological ActivityFPL 55712 is a leukotriene receptor antagonist; inhibits contraction of guinea pig trachealis induced by leukotrienes C4, D4, E4 and F4.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Pharmacological study of the effects of leukotrienes C4, D4, E4 & F4 on guinea pig trachealis: interaction with FPL-55712.
Jones et al.
Pharmacologic properties of FPL 55712 administered by aerosol.
O'Donnell and Welto
Agents Actions, 1984;14:43
Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition.
Folkerts et al.
Citation for FPL 55712
The citations listed below are publications that use Tocris products. Selected citations for FPL 55712 include:
1 Citation: Showing 1 - 1
Pranlukast is a novel small molecule activator of the two-pore domain potassium channel TREK2.
Authors: Wright Et al.
Biochem Biophys Res Commun 2019;520:35
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