Catalog Number: 2276
Chemical Name: 7-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid
Biological Activity
Leukotriene receptor antagonist; inhibits contraction of guinea pig trachealis induced by leukotrienes C4, D4, E4 and F4.
Technical Data
  • M.Wt:
    498.52
  • Formula:
    C27H30O9
  • Solubility:
    Soluble to 50 mM in 100mM NaOH
  • Purity:
    >97%
  • Storage:
    Store at -20°C
  • CAS No:
    40785-97-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition.
    Folkerts et al.
    Eur.J.Pharmacol., 1995;285:R1
  2. Pharmacological study of the effects of leukotrienes C4, D4, E4 & F4 on guinea pig trachealis: interaction with FPL-55712.
    Jones et al.
    Prostaglandins, 1983;26:833
  3. Pharmacologic properties of FPL 55712 administered by aerosol.
    O'Donnell and Welto
    Agents Actions, 1984;14:43

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