FPR1 Antibody Blocking Peptide

Novus Biologicals | Catalog # NB100-56473PEP

Novus Biologicals
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Key Product Details

Applications

Antibody Competition
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Product Specifications

Application Notes

This peptide is useful as a blocking peptide for NB100-56473. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB100-56473 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NB100-56473PEP
Formulation Peptide dissolved in dH20. Contains no BSA.
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: FPR1

Official Gene Symbol: FPR1 Gen Bank Accession Number: NP_002020 Gene ID: 2357 (Human) Gene Map Locus: 19q13.4 (Human) FPR1 is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils and monocytes. FPR1 is a seven transmembrane pertussis toxin-sensitive GPCR and binds to formylated peptides generated by bacteria resulting in leukocyte trafficking to the site of inflammation. Ligand binding to FPR results in activation of multiple effectors including phospholipase C leading to calcium mobilization and PKC activation. Other implications of FPR signaling include polarization of actin cytoskeletion, activation of various integrins, increased cell migration, phagocytosis, degranulation and release of reactive oxygen intermediates.

Long Name

Formyl Peptide Receptor 1

Alternate Names

fMLF-R, FMLP

Gene Symbol

FPR1

Additional FPR1 Products

Product Documents for FPR1 Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for FPR1 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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