Loop diuretic that inhibits the Na+
(NKCC) symporter. Also acts as a non-competitive antagonist at GABAA
receptors with ~ 100-fold greater selectivity for α
6-containing receptors than α
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Residues in transmembrane domains I and II determine γ-aminobutyric acid type AA receptor subtype-selective antagonism by furosemide.
Thompson et al.
Anticonvulsant actions of furosemide in vitro.
Gutschmidt et al.
The citations listed below are publications that use Tocris products. Selected citations for Furosemide include:
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