Inhibitor of G protein βγ
subunit-dependent signaling. Blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells.
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Small molecule disruption of G protein βγ subunit signaling inhibits neutrophil chemotaxis and inflammation.
Lehmann et al.
Phosphoinositide 3-kinase-dependent antagonism in mammalian olfactory receptor neurons.
Ukhanov et al.
The citations listed below are publications that use Tocris products. Selected citations for Gallein include:
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