Gallein

Tocris Bioscience | Catalog # 3090

Inhibitor of Gβ/γ signaling
Tocris Bioscience

Key Product Details

Description

Inhibitor of Gβ/γ signaling
View all G Protein (Heterotrimeric) Inhibitors »

Product Description

Gallein is an inhibitor of G protein βγ subunit-dependent signaling. Blocks PI 3-kinase and Rac1 activation in HL60 cells and chemotaxis in HL60 differentiated cells.

Product Specifications for Gallein

Molecular Weight

364.31

Formula

C20H12O7

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

3',4',5',6'-Tetrahydroxyspiro[isobenzofuran-1(3H),9'-(9H)xanthen]-3-one

CAS Number

2103-64-2

PubChem ID

73685

InChI Key

PHLYOKFVXIVOJC-UHFFFAOYSA-N

SMILES

OC1=CC=C(C(C(C=CC=C5)=C5C(O4)=O)4C(C=CC(O)=C3O)=C3O2)C2=C1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 27.32 75
Ethanol 3.64 10

Preparing Stock Solutions for Gallein

The following data is based on the product molecular weight 364.31.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.75 mM 3.66 mL 18.30 mL 36.60 mL
3.75 mM 0.73 mL 3.66 mL 7.32 mL
7.5 mM 0.37 mL 1.83 mL 3.66 mL
37.5 mM 0.07 mL 0.37 mL 0.73 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 107 publications citing the usage of this product.

Product Documents for Gallein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Gallein

For research use only

Customer Reviews for Gallein (1)

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  • Potent and reliable G protein beta gamma subunits
    Name: Rocco Latorre
    Species: Mouse
    Assay Type: In Vivo
    Cell Line/Tissue: HEK 293 Cells
    Verified Customer | Posted 12/13/2017
    Gallein is not easy to dissolve in solution, to do that is better dissolve gallein in a small quantity of DMSO and then reach your final concentration using Saline. Total DMSO% in the final volume should be no more then 0.5%.
    In-vivo (mouse) and in-vitro (HEK cells) experiments

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