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Galloflavin | CAS No. 1780260-20-9 | Lactate Dehydrogenase A/LDHA Inhibitors
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Description: Lactate dehydrogenase inhibitor; impairs aerobic glycolysis

Chemical Name: 3,8,9,10-Tetrahydroxypyrano[3,2-c][2]benzopyran-2,6-dione potassium salt

Purity: ≥95%

Product Details
Citations (2)

Biological Activity

Galloflavin is an inhibitor of human lactate dehydrogenase (LDH) (Ki values are 5.46 and 15.1 μM for LDH-A and LDH-B, respectively, in competition with pyruvate). Inhibits lactate production and decreases ATP synthesis in PLD/PRF/5 cells; thought to decrease cell viability via impairment of aerobic glycolysis.

Technical Data

Soluble to 5 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Galloflavin

The citations listed below are publications that use Tocris products. Selected citations for Galloflavin include:

2 Citations: Showing 1 - 2

  1. Galloflavin Plus Metformin Treatment Impairs Pancreatic Cancer Cells.
    Authors: Dietmar Et al.
    Anticancer Res  2020;40:153-160
  2. LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
    Authors: Kottakis Et al.
    Nature  2016;539:390


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