Gastrin I (human)

Tocris Bioscience | Catalog # 3006

Selective CCK2 agonist
Tocris Bioscience

Key Product Details

Description

Selective CCK2 agonist
View all CCK2 Receptor Agonists »

Product Description

Gastrin I (human) is an endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist. Gastrin I stimulates gastric acid secretion and has a mitogenic effect on gastric cells. Gastrin I stimulates gastric epithelial cell proliferation and histamine secretion (EC50 values are 6.2 pM and 0.014 nM, respectively). Gastrin I is also used in the culture of stomach, intestine and pancreas organoids. For more information about using Gastrin I in the generation of gastric organoids see the Human Gastric Organoid Culture Protocol.

Product Specifications for Gastrin I (human)

Molecular Weight

2098.22

Formula

C97H124N20O31S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

10047-33-3

PubChem ID

16162108

InChI Key

GKDWRERMBNGKCZ-RNXBIMIWSA-N

SMILES

[H]N1[C@@H](CCC1=O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in 1% Ammonia with sonication

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 83 publications citing the usage of this product.

Product Documents for Gastrin I (human)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Gastrin I (human)

For research use only

Citations for Gastrin I (human)

Customer Reviews for Gastrin I (human) (1)

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  • Stimulation of pancreatic acinar cells
    Name: Louise Reynolds
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Pancreatic acinar cells
    Verified Customer | Posted 06/06/2019
    Used to stimulate pancreatic acinar cells to secrete digestive enzymes in vitro

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