Gastrin I (human)

Catalog # Availability Size / Price Qty
3006/1
Gastrin I (human)
1 Image
Description: Selective CCK2 agonist

Purity: ≥95%

Product Details
Citations (7)
Supplemental Products
Reviews (1)

Biological Activity

Gastrin I (human) is an endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist. Gastrin I stimulates gastric acid secretion and has a mitogenic effect on gastric cells. Gastrin I stimulates gastric epithelial cell proliferation and histamine secretion (EC50 values are 6.2 pM and 0.014 nM, respectively). Gastrin I is also used in the culture of stomach, intestine and pancreas organoids. For more information about using Gastrin I in the generation of gastric organoids see the Human Gastric Organoid Culture Protocol.

Technical Data

M.Wt:
2098.22
Formula:
C97H124N20O31S
Sequence:
XGPWLEEEEEAYGWMDF

(Modifications: X = Glp, Phe-17 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in 1% Ammonia with sonication
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
10047-33-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for Gastrin I (human)

The citations listed below are publications that use Tocris products. Selected citations for Gastrin I (human) include:

7 Citations: Showing 1 - 7

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Stimulation of pancreatic acinar cells
By Louise Reynolds on 06/06/2019
Species: Mouse

Used to stimulate pancreatic acinar cells to secrete digestive enzymes in vitro


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