CCK2 Receptor Agonists

The cholecystokinin₂ receptor (CCK₂ receptor, CCK-B receptor) is a member of the cholecystokinin receptor group of G-protein-coupled receptors that also includes CCK₁. They are located primarily in the brain, spinal cord and stomach where they play a role in anxiety, nociception, neuroleptic activity, gastric acid release, gastric mucosal cell growth and histamine release. The human CCK₂ receptor gene has been localized to chromosome 11 (11p15.4).