Recombinant Human Glutaredoxin 1/GLRX1 Protein

Name: Recombinant Human Glutaredoxin 1/GLRX1 Protein
Brand: Novus Biologicals
SKU: NBC1-22929
Price: 299 USD
Availability: InStock

Novus Biologicals | Catalog # NBC1-22929

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

E. coli

Applications

SDS-PAGE

View all Glutaredoxin 1/GLRX1 Proteins and Enzymes »

Product Specifications

Description

An un-tagged recombinant protein corresponding to the amino acids1-106 of Human Glutaredoxin 1/GLRX1

Source: E.coli

Amino Acid Sequence: MAQEFVNCKI QPGKVVVFIK PTCPYCRRAQ EILSQLPIKQ GLLEFVDITA TNHTNEIQDY LQQLTGARTV PRVFIGKDCI GGCSDLVSLQ QSGELLTRLK QIGALQ

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

11.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Glutaredoxin 1/GLRX1 Protein

SDS-PAGE: Recombinant Human Glutaredoxin 1/GLRX1 Protein [NBC1-22929]

SDS-Page: Recombinant Human Glutaredoxin 1/GLRX1 Protein [NBC1-22929] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation, and Storage

NBC1-22929

Formulation	20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glutaredoxin 1/GLRX1

Description: Glutaredoxin(GRX), also known as thioltransferase, is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Mammalian Glutaredoxin is known to have two isoforms, GRX1 and GRX2. GRX1 is a cytosolic protein, whereas GRX2 is localized both in the mitochondria and nucleus. Glutaredoxin-1 may be involved in a various cellular events such as signal transduction, stress response, and metabolic regulation by regulating the redox status of cellular proteins. Recombinant human Glutaredoxin1 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

GLRX, Thioltransferase

Gene Symbol

GLRX

Additional Glutaredoxin 1/GLRX1 Products

Product Documents for Recombinant Human Glutaredoxin 1/GLRX1 Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human Glutaredoxin 1/GLRX1 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Oxidative Stress

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