Recombinant Human Glutathione Peroxidase 2/GPX2 His Protein

Name: Recombinant Human Glutathione Peroxidase 2/GPX2 His Protein
Brand: Novus Biologicals
SKU: NBP1-78824
Price: 329 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-78824

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all Glutathione Peroxidase 2/GPX2 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-190 of Human Glutathione Peroxidase 2/GPX2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAFIAKSFYD LSAISLDGEK VDFNTFRGRA VLIENVASLC GTTTRDFTQL NELQCRFPRR LVVLGFPCNQ FGHQENCQNE EILNSLKYVR PGGGYQPTFT LVQKCEVNGQ NEHPVFAYLK DKLPYPYDDP FSLMTDPKLI IWSPVRRSDV AWNFEKFLIG PEGEPFRRYS RTFPTINIEP DIKRLLKVAI

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

24.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Glutathione Peroxidase 2/GPX2 His Protein

SDS-PAGE: Recombinant Human Glutathione Peroxidase 2/GPX2 His Protein [NBP1-78824]

SDS-Page: Recombinant Human Glutathione Peroxidase 2/GPX2 Protein [NBP1-78824] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-78824

Formulation	20 mM Tris-HCl buffer (pH7.5), 40% glycerol, 0.15 M NaCl, 1 mM DTT
Preservative	No Preservative
Concentration	0.25 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glutathione Peroxidase 2/GPX2

GPX2, also known as glutathione peroxidase 2, belongs to the glutathione peroxidase family, consisting of eight known glutathione peroxidases (Gpx1-8) in humans. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. GPX2 could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. Recombinant human GPX2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

GIGPX, GPRP, GPX2

Gene Symbol

GPX2

Additional Glutathione Peroxidase 2/GPX2 Products

Product Documents for Recombinant Human Glutathione Peroxidase 2/GPX2 His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human Glutathione Peroxidase 2/GPX2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Oxidative Stress

Redox Enzymes

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