Glycine

Tocris Bioscience | Catalog # 0219

Endogenous potentiator of NMDA receptors
Tocris Bioscience

Key Product Details

Description

Endogenous potentiator of NMDA receptors
View all Additional NMDA Receptor Compounds »

Product Description

One of the major inhibitory neurotransmitters in the mammalian CNS, predominantly active in the spinal cord and brain stem. Also acts as a modulator of excitatory amino acid transmission mediated by NMDA receptors.

Product Specifications for Glycine

Molecular Weight

75.07

Formula

C2H5NO2

Storage

Store at RT

Chemical Name

Aminoethanoic acid

CAS Number

56-40-6

PubChem ID

750

InChI Key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

SMILES

NCC(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 100

Preparing Stock Solutions for Glycine

The following data is based on the product molecular weight 75.07.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 13.32 mL 66.60 mL 133.21 mL
5 mM 2.66 mL 13.32 mL 26.64 mL
10 mM 1.33 mL 6.66 mL 13.32 mL
50 mM 0.27 mL 1.33 mL 2.66 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 411 publications citing the usage of this product.

Product Documents for Glycine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Glycine

For research use only

Customer Reviews for Glycine (1)

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  • Use of glycine as NMDA receptor co-agonist
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 10/19/2019
    For experiments with NMDA receptors use of D-Serine is sometimes better.
    Mixture of 100 microM of glycine + 100 microM NMDA was used to evoke an NMDA receptor response in outside-out patched excised from hippocampal neurons. Glycine displayed a clear co-agonist effect, as expected. Easily soluble, no problem if stored in frozen aliquots for more than half a year.
    Glycine 0219

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