Recombinant Human GNAI3 His Protein

Novus Biologicals | Catalog # NBP1-99039

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
View all GNAI3 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-354 of Human GNAI3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGCTLSA EDKAAVERSK MIDRNLREDG EKAAKEVKLL LLGAGESGKS TIVKQMKIIH EDGYSEDECK QYKVVVYSNT IQSIIAIIRA MGRLKIDFGE AARADDARQL FVLAGSAEEG VMTPELAGVI KRLWRDGGVQ ACFSRSREYQ LNDSASYYLN DLDRISQSNY IPTQQDVLRT RVKTTGIVET HFTFKDLYFK MFDVGGQRSE RKKWIHCFEG VTAIIFCVAL SDYDLVLAED EEMNRMHESM KLFDSICNNK WFTETSIILF LNKKDLFEEK IKRSPLTICY PEYTGSNTYE EAAAYIQCQF EDLNRRKDTK EIYTHFTCAT DTKNVQFVFD AVTDVIIKNN LKECGLY

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human GNAI3 His Protein

SDS-PAGE: Recombinant Human GNAI3 His Protein [NBP1-99039]

SDS-PAGE: Recombinant Human GNAI3 His Protein [NBP1-99039]

SDS-Page: Recombinant Human GNAI3 Protein [NBP1-99039] - 15% SDS-PAGE (3ug)
SDS-PAGE: Recombinant Human GNAI3 His Protein [NBP1-99039]

SDS-PAGE: Recombinant Human GNAI3 His Protein [NBP1-99039]

SDS-Page: Recombinant Human GNAI3 Protein [NBP1-99039] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-99039
Formulation 20 mM Tris-HCl buffer (pH 8.0), 2 mM DTT, 20% glycerol, 100 mM NaCl
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GNAI3

GNAI3 belongs to the G-alpha family and G (i/o/t/z) subfamily. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K+ channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. This protein plays a role in cell division. GNAI3 has been shown to interact with RGS14, RIC8A, RGS18, S1PR1, RGS12, RGS16, RGS19, RGS10 and RGS5. Recombinant human GNAI3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

FLJ26559, G(i) alpha-3, guanine nucleotide binding protein (G protein), alpha inhibiting activitypolypeptide 3,87U6, guanine nucleotide-binding protein G(k) subunit alpha

Gene Symbol

GNAI3

Additional GNAI3 Products

Product Documents for Recombinant Human GNAI3 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human GNAI3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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