Gossypol

Key Product Details

Product Description

Gossypol is a lipophilic agent derived from cottonseed. Exhibits multiple biological effects including antifertility and anticancer activity. Proapoptotic; downregulates Bcl-2 and Bcl-XL.

R-enantiomer also available.

Product Specifications for Gossypol

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Gossypol

The following data is based on the product molecular weight 518.56.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	7.71 mL	38.57 mL	77.14 mL
1.25 mM	1.54 mL	7.71 mL	15.43 mL
2.5 mM	0.77 mL	3.86 mL	7.71 mL
12.5 mM	0.15 mL	0.77 mL	1.54 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.

• Vander Jagt Gosspyol: prototype of inhibitors targeted to dinucleotide folds. Curr.Med.Chem. 2000 PMID: 10702620
• Zhang Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells. Biochem.Pharmacol. 2003 PMID: 12818369
• Coutinh Gossypol: a contraceptive for men. Contraception 2002 PMID: 12020773

Product Documents for Gossypol