Chemical Name: N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide
Biological Activity Highly selective CB2 receptor agonist; Ki values are 0.037 and 363 nM for CB2 and CB1 receptors respectively. Increases P-ERK1/2 expression in HL-60 cells in vitro. More recently shown to be CB2 receptor inverse agonist/antagonist in cAMP, GTPγS and β-arrestin recruitment assays.
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at RT
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