GR 64349

Tocris Bioscience | Catalog # 1668

Potent, selective NK2 agonist
Tocris Bioscience
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Key Product Details

Description

Potent, selective NK2 agonist

Product Description

GR 64349 is a potent and selective tachykinin NK2 receptor agonist (EC50 = 3.7 nM in rat colon). Displays > 1000- and > 300-fold selectivity over NK1 and NK3 receptors respectively. Active in vivo.

Licensing Information

Sold for research purposes under agreement from GlaxoSmithKline

Product Specifications for GR 64349

Molecular Weight

921.12

Formula

C42H68N10O11S

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

137593-52-3

PubChem ID

5311135

InChI Key

HVUNRXRFMQDMBO-BPZYSUIOSA-N

SMILES

[H]N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NC1CCN([C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solubility Soluble to 1mg/ml in water

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 17 publications citing the usage of this product.

Product Documents for GR 64349

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for GR 64349

For research use only

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