GR 64349
Tocris Bioscience | Catalog # 1668
Product Description
GR 64349 is a potent and selective tachykinin NK2 receptor agonist (EC50 = 3.7 nM in rat colon). Displays > 1000- and > 300-fold selectivity over NK1 and NK3 receptors respectively. Active in vivo.Licensing Information
Sold for research purposes under agreement from GlaxoSmithKline
Product Specifications for GR 64349
Molecular Weight
Formula
Storage
Purity
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 17 publications citing the usage of this product.
- Chizh Endogenous modulation of excitatory amino acid responsiveness by tachykinin NK1 and NK2 receptors in the rat spinal cord. Br.J.Pharmacol. 1995 PMID: 7582497
- Deal Conformationally constrained tachykinin analogues: potent and highly selective neurokinin NK-2 receptor agonists. J.Med.Chem. 1992 PMID: 1331460
- Chang Tachykinin receptor subtypes in the isolated guinea pig heart and their role in mediating responses to neurokinin A. J.Pharmacol.Exp.Ther. 2000 PMID: 10871306
Product Documents for GR 64349
Certificate of Analysis
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Product Specific Notices for GR 64349
For research use only
Citations for GR 64349
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