GR 89696 fumarate
Chemical Name: 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate
Biological ActivityGR 89696 fumarate is a highly potent and selective κ-opioid agonist (IC50 = 0.04 nM) that may be selective for the putative κ2 receptor. Anti-nociceptive and neuroprotective in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Neuroprotective actions of GR89696, a highly potent and selective κ-opioid receptor agonist.
Birch et al.
GR89,696: a potent κ-opioid agonist with subtype selectivity in rhesus monkeys.
Butelman et al.
A potent new class of κ-receptor agonist: 4-substituted 1-(arylacetyl)-2-[(dialkylamino)methyl]piperazines.
Naylor et al.
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