GR 89696 fumarate

Key Product Details

Product Description

GR 89696 fumarate is a highly potent and selective κ-opioid agonist (IC₅₀ = 0.04 nM) that may be selective for the putative κ₂ receptor. Anti-nociceptive and neuroprotective in vivo.

Product Specifications for GR 89696 fumarate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for GR 89696 fumarate

The following data is based on the product molecular weight 530.40.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.89 mL	9.43 mL	18.85 mL
5 mM	0.38 mL	1.89 mL	3.77 mL
10 mM	0.19 mL	0.94 mL	1.89 mL
50 mM	0.04 mL	0.19 mL	0.38 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

• Butelman GR89,696: a potent κ-opioid agonist with subtype selectivity in rhesus monkeys. J.Pharmacol.Exp.Ther. 2001 PMID: 11504802
• Naylor A potent new class of κ-receptor agonist: 4-substituted 1-(arylacetyl)-2-[(dialkylamino)methyl]piperazines. J.Med.Chem. 1993 PMID: 8393489
• Birch Neuroprotective actions of GR89696, a highly potent and selective κ-opioid receptor agonist. Br.J.Pharmacol. 1991 PMID: 1657267

Product Documents for GR 89696 fumarate