Granisetron hydrochloride

Catalog # Availability Size / Price Qty
2903/10
2903/50
Granisetron hydrochloride | CAS No. 107007-99-8 | 5-HT3 Receptor Antagonists
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Description: 5-HT3 antagonist
Alternative Names: BRL 43694

Chemical Name: 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride

Purity: ≥99%

Product Details
Citations (4)
Supplemental Products
Reviews

Biological Activity

5-HT3 receptor antagonist that possesses potent antiemetic activity.

Technical Data

M.Wt:
348.87
Formula:
C18H24N4O.HCl
Solubility:
Soluble to 100 mM in water and to 10 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
107007-99-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Selective and functional 5-hydroxytryptamine3 receptor antagonism by BRL 43694 (granisetron).
    Sanger and Nelson
    Eur.J.Pharmacol., 1989;159:113
  2. Granisetron. A review of its pharmacological properties and therapeutic use as an antiemetic.
    Plosker and Goa
    Drugs, 1991;42:805
  3. Anti-emetic effect of ondans. and granis. after exposure to mixed neutron and gamma irradiation.
    Martin et al.
    Rad.Res., 1998;149:631

Product Datasheets

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Citations for Granisetron hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Granisetron hydrochloride include:

4 Citations: Showing 1 - 4

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