Granisetron hydrochloride

Key Product Details

Product Description

Granisetron hydrochloride is a 5-HT₃ receptor antagonist that possesses potent antiemetic activity.

Product Specifications for Granisetron hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Granisetron hydrochloride

The following data is based on the product molecular weight 348.87.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.87 mL	14.33 mL	28.66 mL
5 mM	0.57 mL	2.87 mL	5.73 mL
10 mM	0.29 mL	1.43 mL	2.87 mL
50 mM	0.06 mL	0.29 mL	0.57 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 11 publications citing the usage of this product.

• Plosker and Goa Granisetron. A review of its pharmacological properties and therapeutic use as an antiemetic. Drugs 1991 PMID: 1723376
• Martin Anti-emetic effect of ondans. and granis. after exposure to mixed neutron and gamma irradiation. Rad.Res.
• Sanger and Nelson Selective and functional 5-hydroxytryptamine₃ receptor antagonism by BRL 43694 (granisetron). Eur.J.Pharmacol. 1989 PMID: 2540014

Product Documents for Granisetron hydrochloride