GRASP1 Antibody

Catalog # Availability Size / Price Qty
Detection of GRASP by Western Blot.
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Product Details
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GRASP1 Antibody Summary

Species Reactivity
Human, Mouse, Rat, Bovine, Canine
This antibody is specific for the 95 kDa GRASP in Western blots of rat cerebellar lysates.
Polyclonal Rabbit IgG
Antigen Affinity-purified
Peptide corresponding to amino acid residues from the C‑terminal region of rat GRASP, conjugated to keyhole limpet hemocyanin (KLH)
100 μL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.


Recommended Concentration
Western Blot
1:1000 dilution
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of GRASP antibody by Western Blot. View Larger

Detection of GRASP by Western Blot. Western blot of rat cerebellar lysate showing the specific immunolabeling of the approximately 95 kDa GRASP protein.

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Preparation and Storage

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
For long-term storage, ≤‑20° C is recommended. Product is stable at ≤ ‑20° C for at least 1 year.

Background: GRASP1

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo. Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity.

  1. Scannevin, R.H. and R.L. Huganir (2000) Nat. Rev. Neurosci. 1:133.
  2. Ye, B. et al. (2000) Neuron 26:603.
Long Name
GRIP1 Associated Protein 1
Entrez Gene IDs
56850 (Human); 54645 (Mouse); 116493 (Rat)
Alternate Names
DKFZp434P0630; GRASP1; GRASP-1MGC126595; GRIP1 associated protein 1; GRIP1-associated protein 1; GRIPAP1; KIAA1167MGC126593; MPMGp800B12492Q3

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