Biological ActivityGRK2i is a GRK2 inhibitory polypeptide that specifically inhibits Gβγ activation of GRK2. Corresponds to the Gβγ-binding domain and acts as a cellular Gβγ antagonist.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates Gβγ-mediated signaling.
Koch et al.
A βγ dimer derived from G13 transduces the angiotensin AT1 receptor signal to stimulation of Ca2+ channels in rat portal vein myocytes.
Macrez et al.
Two distinct mechanisms mediate acute μ-opioid receptor desensitization in native neurons.
Dang et al.
Citations for GRK2i
The citations listed below are publications that use Tocris products. Selected citations for GRK2i include:
2 Citations: Showing 1 - 2
G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity.
Authors: Stott Et al.
Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction.
Authors: Sierra-Fonseca Et al.
BMC Neurosci 2014;15:132
No product specific FAQs exist for this product, however you mayView all Peptide FAQs
Reviews for GRK2i
There are currently no reviews for this product. Be the first to review GRK2i and earn rewards!
Have you used GRK2i?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image