GRP (human)

  ( 4 citations )    
Product Datasheet
Catalog Number:1789
Alternate Names:Gastrin-releasing peptide (human)
Chemical Name:
Product Details
Citations (4)
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Reviews
Biological Activity
Mammalian bombesin-like peptide neurotransmitter that is an agonist for the gastrin-releasing peptide receptor (GRPR). GRP has been reported to activate GABAergic interneurons in the amygdala leading to increased GABA release and fear suppression in mice in vivo. Also involved in mitogenesis, and GI tract and appetite regulation.
Technical Data
  • M.Wt:
    2859.4
  • Formula:
    C130H204N38O31S2
  • Sequence:
    VPLPAGGGTVLTKMYPRGNHWAVGHLM

    (Modifications: Met-27 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    93755-85-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for GRP (human) include:

4 Citations: Showing 1 - 4
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  1. Gastrin-releasing peptide receptor mediates the excitation of preoptic GABAergic neurons by bombesin
    Authors: Blais Et al.
    Neuroscience Letters  2016;633:262
  2. Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates.
    Authors: Lee and Ko
    Int J Inflam  2015;5:11676
  3. Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concerns.
    Authors: Solorzano Et al.
    Sci Rep  2015;35:648
  4. Enhanced autophagy blocks angiogenesis via degradation of gastrin-releasing peptide in neuroblastoma cells.
    Authors: Kim Et al.
    J Neurosci  2013;9:1579

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