GS 6201

Catalog # Availability Size / Price Qty
4727/10
4727/50
Cat.No. 4727 - GS 6201 | C21H21F3N6O2 | CAS No. 752222-83-6
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Description: Selective A2B antagonist
Alternative Names: CVT 6883

Chemical Name: 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione

Product Details
Citations (1)
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Biological Activity

Selective antagonist of adenosine A2B receptors (Ki values are 22, 1070, 1940 and 3280 nM for human A2B, A3, A1 and A2A receptors respectively). Attenuates allergen-, NECA- and AMP-induced airway reactivity in an allergic mouse model of asthma. Also shown to attenuate the inflammatory response during acute myocardial infarction in mice; reduces caspase-1 activity in the heart.

Technical Data

Formula:
C21H21F3N6O2
Solubility:
Soluble to 5 mM in DMSO
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS No:
752222-83-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Product Datasheets

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Citation for GS 6201

The citations listed below are publications that use Tocris products. Selected citations for GS 6201 include:

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