Chemical Name: 4-Hydroxy-2-[(1E)-[4-(1-methylethyl)phenyl]methylene]hydrazide
Biological ActivitySelective agonist at estrogen-related receptors ERRβ and ERRγ. Displays selectivity over ERRα and the classical estrogen receptors.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRβ and ERRγ.
Zuercher et al.
Estrogen-related receptors as emerging targets in cancer and metabolic disorders.
Ariazi and Jordan
X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
Wang et al.
Citation for GSK 4716
The citations listed below are publications that use Tocris products. Selected citations for GSK 4716 include:
1 Citation: Showing 1 - 1
Bisphenol A exposure during early development induces sex-specific changes in adult zebrafish social interactions.
Authors: Weber Et al.
J Toxicol Environ Health A 2014;78:50
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