GSK LSD 1 dihydrochloride

Key Product Details

Product Description

GSK LSD 1 dihydrochloride is a potent and selective lysine specific demethylase 1 (LSD1) inhibitor (IC₅₀ = 16 nM). Exhibits >1000-fold selectivity for LSD1 over closely related enzymes including LSD2, MAO-1 and MAO-B. Inhibits cancer cell line growth in vitro.

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the GSK LSD 1 probe summary on the SGC website.

Product Specifications for GSK LSD 1 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for GSK LSD 1 dihydrochloride

The following data is based on the product molecular weight 289.24.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.46 mL	17.29 mL	34.57 mL
5 mM	0.69 mL	3.46 mL	6.91 mL
10 mM	0.35 mL	1.73 mL	3.46 mL
50 mM	0.07 mL	0.35 mL	0.69 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

There are currently no references for this product.

Product Documents for GSK LSD 1 dihydrochloride