-adrenoceptor agonist (Kd
= 31 nM). Displays 60-fold selectivity over α2B
-adrenoceptors. Also available as part of the α2-Adrenoceptor Tocriset™
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Alpha-2a/d adrenoceptor subtype stimulation by guanfacine increases osmolar clearance.
Intengan and Smyth
Delineation of rat kidney α2A- and α2B-adrenoceptors with [3H]RX821002 radioligand binding: computer modelling reveals that guanfacine is an α2A -selective compound.
Uhlen and Wikberg
Synthesis of S-[3-(4(5)-imidazolyl)propyl]-N-[2-(4-[125I]-iodophenylethyl]isothiourea sulfate [125I]-iodophenpropit), a new probe for histamine H3 receptor binding sites.
Menge et al.
J.Labelled Comp.Radiopharm. XXXI, 1992;10:781
The citations listed below are publications that use Tocris products. Selected citations for Guanfacine hydrochloride include:
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