GW 1929 hydrochloride

  ( 2 citations )    
Product Datasheet
Catalog Number:1664
Chemical Name:N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride
Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity
Highly selective orally active peroxisome proliferator-activated receptor (PPAR)γ agonist (pEC50 values are 8.05, < 4 and < 4 for human PPARγ, PPARα and PPARδ receptors respectively). Decreases glucose, fatty acid and triglyceride levels following oral administration in vivo.
Technical Data
  • M.Wt:
    532.03
  • Formula:
    C30H29N3O4.HCl
  • Solubility:
    Soluble to 100 mM in ethanol with gentle warming and to 50 mM in water
  • Purity:
    >98
  • Storage:
    Desiccate at +4°C
  • CAS No:
    1217466-21-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold for research purposes under agreement from GlaxoSmithKline
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for GW 1929 hydrochloride include:

2 Citations: Showing 1 - 2
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  1. Nicotinic acid receptor GPR109A is down-regulated in human macrophage-derived foam cells.
    Authors: Chai Et al.
    PLoS One  2013;8:e62934
  2. Murine atopic dermatitis responds to peroxisome proliferator-activated receptors α and β/δ (but not γ) and liver X receptor activators.
    Authors: Hatano Et al.
    Endocrinology  2010;125:160

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