Home / Lysophosphatidic Acid (LPA) Receptor Antagonists / H2L 5765834

H2L 5765834

Catalog #: 4870
1 Citation Datasheet / COA / SDS
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4870/50
H2L 5765834 | CAS No. 420841-84-5 | Lysophosphatidic Acid (LPA) Receptor Antagonists
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Description: LPA1,3,5 antagonist

Chemical Name: 2,3-Dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

H2L 5765834 is an antagonist of the lysophosphatidic acid receptors LPA1, LPA5 and LPA3 (IC50 values are 94, 463 and 752 nM respectively). Exhibits no effect at LPA2 or LPA4 receptors.

Technical Data

M.Wt:
404.33
Formula:
C21H12N2O7
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
420841-84-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for H2L 5765834

The citations listed below are publications that use Tocris products. Selected citations for H2L 5765834 include:

1 Citation: Showing 1 - 1

  1. Lysophosphatidic acid-induced itch is mediated by signalling of LPA5 receptor, phospholipase D and TRPA1/TRPV1.
    Authors: Kittaka Et al.
    J Physiol  2017;595:2681

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VersaClone cDNA Plasmids

Human LPAR1/LPA1/EDG-2 (NP_001392) VersaClone cDNA

RDC0315

Human LPAR3/LPA3/EDG-7 (NP_036284) VersaClone cDNA

RDC0319

Human LPAR5/LPA5/GPR92 (NP_065133) VersaClone cDNA

RDC0455

Mouse LPAR1/LPA1/EDG-2 (NP_034466) VersaClone cDNA

RDC0565

Mouse LPAR3/LPA3/EDG-7 (NP_075359) VersaClone cDNA

RDC0561

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