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3 results for "Lysophosphatidic Acid (LPA) Receptor Antagonists" in Products
Lysophosphatidic Acid (LPA) Receptor Antagonists
Lysophosphatidic acid (LPA) receptors are a group of G-protein-coupled receptors that are currently divided into six subtypes: LPA1, LPA2, LPA3, LPA4, LPA5 and LPA6. They belong to a family of lysophospholipid receptors that include sphingosine 1-phosphate (S1P) receptors.
Originally identified as members of the endothelial differentiation gene (edg) family, the gene names for the LPA receptors have recently been updated to LPAR1-LPAR3, with LPAR4-LPAR6 also having been updated to reflect ...
LPA5 receptor antagonist
| Chemical Name: | 5-(3-Chloro-4-cyclohexylphenyl)-1-(3-methoxyphenyl)-1H-pyrazole-3-carboxylic acid |
| Purity: | ≥98% |
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Potent LPA1 antagonist
| Chemical Name: | 1-[4'-[4-Methyl-5-[[[(1R)-1-phenylethoxy]carbonylamino]-1H-1,2,3-triazol-1-yl][1,1'-biphenyl]-4-yl]cyclopropanecarboxylic acid |
| Purity: | ≥98% |
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Selective, brain penetrant LPA5 antagonist
| Chemical Name: | 6,7-Dimethoxy-2-(5-methyl-1,2-benzisoxazol-3-yl)-4-(1-piperidinylcarbonyl)-1(2H)-isoquinolinone |
| Purity: | ≥98% |
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