Recombinant Human HDDC3 His Protein

Name: Recombinant Human HDDC3 His Protein
Brand: Novus Biologicals
SKU: NBP1-72506
Price: 929 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-72506

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all HDDC3 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-140 of Human HDDC3

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSEAAQLLE AADFAARKHR QQRRKDPEGT PYINHPIGVA RILTHEAGIT DIVVLQAALL HDTVEDTDTT LDEVELHFGA QVRRLVEEVT DDKTLPKLER KRLQVEQAPH SSPGAKLVKL ADKLYNLRDL NRCTPEVKIQ

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

17.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human HDDC3 His Protein

SDS-PAGE: Recombinant Human HDDC3 His Protein [NBP1-72506]

SDS-Page: Recombinant Human HDDC3 Protein [NBP1-72506] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-72506

Formulation	20 mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.15 M NaCl, 1 mM DTT
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HDDC3

HDDC3, also known as guanosine-3',5'-bis(diphosphate)-pyrophosphohydrolase MESH1, contains an active site for ppGpp hydrolysis and a conserved His-Asp-box motif for Mn(2+) binding. Consistent with these structural data, HDDC3 efficiently catalyzes hydrolysis of guanosine 3',5'-diphosphate (ppGpp) both in vitro and in vivo. HDDC3 also suppresses SpoT-deficient lethality and RelA-induced delayed cell growth in bacteria. Recombinant human HDDC3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Alternate Names

(ppGpp)ase, EC 3.1.7.2, guanosine-3'-5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, HD domain containing 3, HD domain-containing protein 3, MESH1, Metazoan SpoT homolog 1, metazoan SpoT homolog-1, MGC45386, Penta-phosphate guanosine-3'-pyrophosphohydrolase

Gene Symbol

HDDC3

Additional HDDC3 Products

Product Documents for Recombinant Human HDDC3 His Protein

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Product Specific Notices for Recombinant Human HDDC3 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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