HIP1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-81593

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all HIP1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPADSLTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HIP1 Antibody - BSA Free

Western Blot: HIP1 Antibody [NBP1-81593]

Western Blot: HIP1 Antibody [NBP1-81593]

Western Blot: HIP1 Antibody [NBP1-81593] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue
Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593] - Staining of human testis using Anti-HIP1 antibody NBP1-81593.
Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593] - Staining in human testis and liver tissues using anti-HIP1 antibody. Corresponding HIP1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593] - Staining of human colon, kidney, liver and testis using Anti-HIP1 antibody NBP1-81593 (A) shows similar protein distribution across tissues to independent antibody NBP1-81592 (B).
Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593] - Staining of human colon.
Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593] - Staining of human kidney.
Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593]

Immunohistochemistry-Paraffin: HIP1 Antibody [NBP1-81593] - Staining of human liver using Anti-HIP1 antibody NBP1-81593.

Applications for HIP1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HIP1

Huntingtin Interacting Protein (HIP1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin's disease. Huntingtin's is a neurodegenerate disease caused by the expansion of a polymorphic glutamine tract in Huntingtin.

In addition to playing a role in Huntingtin disease, HIP1 is likely to be involved in the recruitment of clathrin coats to lipid membranes, and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.

Alternate Names

HIP-1, HIP-I, huntingtin interacting protein 1, huntingtin-interacting protein 1, Huntingtin-interacting protein I, ILWEQ, MGC126506

Gene Symbol

HIP1

Additional HIP1 Products

Product Documents for HIP1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for HIP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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