Chemical Name: 2-(4-Imidazolyl)ethylamine dihydrochloride
Biological ActivityHistamine dihydrochloride is an endogenous agonist at histamine receptors (H1-4). Released from mast cells and basophils and exhibits inflammatory, vasodilatory and bronchoconstrictory activity. Stimulates gastric acid secretion and acts as a neurotransmitter in vivo.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Complete Your Experiment
International union of pharmacology. XIII. Classification of histamine receptors.
Hill et al.
The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines.
Thurmond et al.
Nat.Rev.Drug Discov., 2008;7:41
Histamine and histamine intolerance.
Maintz and Novak
Citations for Histamine dihydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Histamine dihydrochloride include:
4 Citations: Showing 1 - 4
Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop.
Authors: Chen Et al.
Cell Stem Cell 2017;21:747
Pronociceptive and Antinociceptive Effects of Bupren. in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude.
Authors: Gerhold Et al.
J Neurosci 2015;35:9580
Hippocampal-Dependent Antidepressant Action of the H3 Receptor Antagonist Clobenpropit in a Rat Model of Depression.
Authors: Femenia Et al.
Int J Neuropsychopharmacol 2015;18
Gαq/11-mediated intracellular calcium responses to retrograde flow in endothelial cells.
Authors: Melchior and Frangos
Acta Pharmacol Sin 2012;303:C467
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
VersaClone cDNA Plasmids
Reviews for Histamine dihydrochloride
There are currently no reviews for this product. Be the first to review Histamine dihydrochloride and earn rewards!
Have you used Histamine dihydrochloride?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image