Recombinant Human HMGA1 His Protein

Novus Biologicals | Catalog # NBP1-72385

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
View all HMGA1 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 1-107 of Human HMGA1

Source: E.coli

Amino Acid Sequence: MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPVSPGTA LVGSQKEPSE VPTPKRPRGR PKGSKNKGAA KTRKTTTTPG RKPRGRPKKL EKEEEEGISQ ESSEEEQLEH HHHHH

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

12.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human HMGA1 His Protein

SDS-PAGE: Recombinant Human HMGA1 His Protein [NBP1-72385]

SDS-PAGE: Recombinant Human HMGA1 His Protein [NBP1-72385]

SDS-Page: Recombinant Human HMGA1 Protein [NBP1-72385]

Formulation, Preparation, and Storage

NBP1-72385
Formulation 20 mM Tris-HCl buffer (pH 8.0), 50% glycerol, 0.2 M NaCl
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HMGA1

High mobility group protein HMG-I/HMG-Y, also known as HMGA1, is a member of the non-histone chromosomal high mobility group protein (HMG) family. HMGA1 consists of a highly conserved AT-hook DNA-binding domain that mediates binding to AT-rich sequences in the minor groove of chromosomal DNA. It functions as architectural chromatin-binding transcription factor altering the conformation of DNA by modulating nuclear protein-DNA complexes. It is involved in many cellular processes including growth regulation, viral induction of beta-IFN gene and regulation of inducible gene transcription. Recombinant human HMGA1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

high mobility group AT-hook 1, High mobility group AT-hook protein 1, High mobility group protein A1, high mobility group protein HMG-I/HMG-Y, High mobility group protein R, high-mobility group (nonhistone chromosomal) protein isoforms I and Y, HMGA1A, HMG-I(Y), HMGIYMGC12816, HMG-R, MGC4242, MGC4854, nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y

Gene Symbol

HMGA1

Additional HMGA1 Products

Product Documents for Recombinant Human HMGA1 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human HMGA1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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