HMGN1/HMG14 Antibody

Novus Biologicals | Catalog # NBP2-14842

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Porcine, Bovine, Canine, Primate, Rabbit

Predicted:

Chimpanzee (94%), Monkey (100%), Orangutan (94%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all HMGN1 Primary Antibodies »

Product Specifications

Immunogen

A portion of amino acids 1-50 from human HMG14 was used as the immunogen for this antibody.

Reactivity Notes

Predicted to react with Chimpanzee, Chicken, Guinea Pig, Opossum. The HMG14 amino acid sequence used as immunogen for this antibody is 83% in Opossum, Mouse, and Rat.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for HMGN1/HMG14 Antibody

Western Blot: HMGN1/HMG14 Antibody [NBP2-14842]

Western Blot: HMGN1/HMG14 Antibody [NBP2-14842]

Western Blot: HMG14 Antibody [NBP2-14842] - Analysis of HMG14 in Daudi lysate in the 1) absence and 2) presence of immunizing peptide probed with 2 ug/ml of HMG14 antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Applications for HMGN1/HMG14 Antibody

Application
Recommended Usage

Western Blot

2 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS containing 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HMGN1

HMG14, also known as HMGN1, along with HMG17 and HMGN2 are non-histone proteins that bind nucleosomal cores and nucleosomal DNA (1, 2). Like transcription regulatory factors, they may travel to and from the nucleus or at least dissociate and bind again to DNA promoting the folding and unfolding of DNA regulatory sequences exposed to or hiding from binding sites of regulatory factors (3). Both HMG14 and HMG17 affect remodeling and therefore regulate gene activation or repression through transcription factor activity or DNA repair mechanisms (4, 5). Antibody to HMG14 aids in identifying its role in epigenetic related studies.

Long Name

High Mobility Group Nucleosome Binding Domain 1

Alternate Names

HMG14

Gene Symbol

HMGN1

UniProt

NP_004956.5 (Human)

Additional HMGN1 Products

Product Documents for HMGN1/HMG14 Antibody

Certificate of Analysis

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Product Specific Notices for HMGN1/HMG14 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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