Inhibitor of protein synthesis. Blocks elongation phase of translation by binding to the 60-S ribosome subunit. Antileukemic.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Apoptotic response to homoharringtonine in human wt p53 leukemic cells is independent of reactive oxygen species generation and implicates Bax translocation, mitochondrial cytochrome c release and caspase activation.
Cai et al.
Inhibition of translation in eukaryotic systems by harringtonine.
Fresno et al.
Homoharringtonine: an effective new natural product in cancer chemotherapy.
Zhou et al.
The citations listed below are publications that use Tocris products. Selected citations for Homoharringtonine include:
Showing Results 1 - 2 of 2