Human ADAM19 Biotinylated Antibody

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Product Details
Supplemental Products

Human ADAM19 Biotinylated Antibody Summary

Species Reactivity
Detects human ADAM19 in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse ADAM19 is observed and less than 5% cross-reactivity with recombinant human (rh) ADAM8, rhADAM12, and rhADAM33 is observed.
Polyclonal Sheep IgG
Antigen Affinity-purified
Chinese hamster ovary cell line CHO-derived recombinant human ADAM19
Accession # Q9H013
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Human ADAM19

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
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Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: ADAM19

ADAM19 (a disintegrin and metalloprotease 19; also MADDAM and Meltrin-beta ) is a 95‑100 kDa member of the M12B peptidase family of enzymes. It is expressed on multiple cell types including monocytes, fibroblasts, osteoblasts and dendritic cells. The human ADAM19 proenzyme is a 931 amino acid (aa) type I transmembrane protein. It contains a 178 aa cleavable proregion (aa 26‑203) and a 497 aa extracellular domain (ECD) (aa 204‑702). The ECD contains a metalloprotease domain (aa 211‑409), a disintegrin region (aa 417‑503) and a Cys-rich domain (aa 504‑650). The ECD circulates in plasma bound to 700 kDa alpha 2-Macroglobulin. One splice variant shows an alternate start site at Met71, while two isoforms show variations after Lys902. Over aa 205‑702, human ADAM19 is 87% aa identical to mouse ADAM19.

Long Name
A Disintegrin and Metalloprotease-like Domain 19
Entrez Gene IDs
8728 (Human); 11492 (Mouse)
Alternate Names
a disintegrin and metalloproteinase domain 19 (meltrin beta); ADAM 19; ADAM metallopeptidase domain 19; ADAM19; disintegrin and metalloproteinase domain-containing protein 19; EC 3.4.24; EC 3.4.24.-; MADDAM; Meltrin beta; meltrin-beta; Metalloprotease and disintegrin dendritic antigen marker; MLTNBmeltrin beta

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