Human AGTR-2 PE-conjugated Antibody

  • Species Reactivity
  • Specificity
    Detects human AGTR‑2. Stains human AGTR-2-transfected cells but not irrelevant transfectants.
  • Source
    Monoclonal Mouse IgG2B Clone # 364805
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    HEK293 human embryonic kidney cell line transfected with human AGTR-2
    Accession # P50052
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of AGTR-2 in NS0 Mouse Cell Line Transfected with AGTR-2 by Flow Cytometry. NS0 mouse myeloma cell line transfected with AGTR-2 was stained with Mouse Anti-Human AGTR-2 PE-conjugated Monoclonal Antibody (Catalog # FAB3659P, filled histogram) or isotype control antibody (Catalog # IC0041P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: AGTR-2
AGTR-2, also known as AT2, is a 7-transmembrane protein that belongs to family 1 of G protein-coupled receptors. Both AGTR-2 and AGTR-1 bind Angiotensin II and function in the control of hemodynamics. In contrast to AGTR-1, which promotes vasoconstriction and cell proliferation, AGTR-2 inhibits growth and promotes apoptosis. In addition, Angiotensin II-induced AGTR-2 signaling induces the release of nitric oxide in the heart, kidney, and brain and participates in tissue morphogenesis and repair. Human AGTR-2 shares 92% amino acid sequence identity with mouse and rat AGTR-2.
  • Long Name:
    Angiostensin II Type 2 Receptor
  • Entrez Gene IDs:
    186 (Human); 11609 (Mouse); 24182 (Rat)
  • Alternate Names:
    AGTR2; angiotensin II receptor, type 2; Angiotensin II type-2 receptor; angiotensin receptor 2; AT2; AT2ATGR2; AT2R; MRX88; MRX88type-2 angiotensin II receptor
Related Research Areas
Isotype Controls
Description Application Cat# Citations Images  

Mouse IgG2B PE-conjugated Antibody

Ctrl IC0041P 12  
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Staining Reagents
Description Application Cat# Citations Images  

Flow Cytometry Staining Buffer (1X)

Flow FC001 3
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Flow Cytometry Mouse Lyse Buffer (10X)

Flow FC003 1
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Flow Cytometry Human Lyse Buffer (10X)

Flow FC002 1
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