APH1B encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. APH1B represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Human APH1B (NP_112591) VersaClone cDNA
R&D Systems | Catalog # RDC0365
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Background: APH1B
Long Name
Anterior Pharynx Defective 1 Homolog B
Alternate Names
PSFL
Gene Symbol
APH1B
UniProt
Additional APH1B Products
Product Documents for Human APH1B (NP_112591) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human APH1B (NP_112591) VersaClone cDNA
For research use only
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