Human ARTS1 (AAF07395) VersaClone cDNA

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Human ARTS1 (AAF07395) VersaClone cDNA
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Human ARTS1 (AAF07395) VersaClone cDNA Summary


Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: Aminopeptidase PILS/ARTS1

The name of Aminopetidase PILS (Puromycin-insensitive Leucyl-specific) describes the two basic properties of this zinc metalloproteinase in vitro. Also known as ALAP (Adipocyte-derived Leucine Aminopeptidase), Aminopeptidase regulator of TNFR1 shedding 1 (ARTS1), and ER Aminopeptidase ERAP1 or ERAAP, it is encoded by the ARTS1 gene. Aminopeptidase PILS is thought to regulate antigen presentation, promote TNFR1 and IL-6 R ectodomain shedding, and may be associated with hypertension.

Long Name
Aminopeptidase Puromycin-insensitive Leucyl-specific
Entrez Gene IDs
51752 (Human); 80898 (Mouse); 102146570 (Cynomolgus Monkey)
Alternate Names
Adipocyte-derived leucine aminopeptidase; A-LAP; A-LAPALAP; Aminopeptidase PILS; ARTS1; ARTS1aminopeptidase regulator of TNFR1 shedding; ARTS-1PILSAP; EC 3.4.11; EC 3.4.11.-; EC; endoplasmic reticulum aminopeptidase 1; endoplasmic reticulum aminopeptidase associated with antigen processing; ERAAP1; ERAP1; KIAA0525APPILS; PILS-AP; PILS-APERAAP; Puromycin-insensitive leucyl-specific aminopeptidase; Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator


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