Human Asparagine Synthetase/ASNS (NP_001664) VersaClone cDNA

Name: Human Asparagine Synthetase/ASNS (NP_001664) VersaClone cDNA
Brand: R&D Systems
SKU: RDC2452
Price: 270 USD
Availability: InStock

R&D Systems | Catalog # RDC2452

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_001664

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Asparagine Synthetase/ASNS

Asparagine synthetase (AS) is a housekeeping enzyme responsible for the production of asparagine from aspartate and glutamine. Most mammalian cells express AS and regulate the level of activity in response to the concentration of asparagine in the medium. Certain tumor cells in contrast, exhibit little or no AS activity and rely on the surrounding medium as a source of exogenous asparagines (1). Therefore tumor cells may be selectively killed by a chemotherapeutic drug using asparaginase. This approach has been exploited in the treatment of certain cancers like childhood acute lymphoblastic leukemia (2).

Long Name

ASNS

Alternate Names

ASNSD, EC 6.3.5.4, Glutamine Dependent Asparagine Synthetase, TS11 Cell Cycle Control Protein

Entrez Gene IDs

440 (Human); 27053 (Mouse); 25612 (Rat)

Gene Symbol

ASNS

UniProt

NP_001664

Additional Asparagine Synthetase/ASNS Products

Product Documents for Human Asparagine Synthetase/ASNS (NP_001664) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Human Asparagine Synthetase/ASNS (NP_001664) VersaClone cDNA

For research use only

Related Research Areas

Cell Cycle

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