Human B3GalT4 (NP_003773) VersaClone cDNA

R&D Systems | Catalog # RDC2263

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Key Product Details

Species

Human

Accession Number

NP_003773

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: B3GalT4

B3GALT4 is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis. [provided by RefSeq]

Long Name

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4

Alternate Names

Beta-1,3-GalTase 4, Beta3Gal-T4, Beta3GalT4, Gal-T2, Galt2, GALT4

Entrez Gene IDs

8705 (Human); 54218 (Mouse); 171079 (Rat)

Gene Symbol

B3GALT4

UniProt

NP_003773

Additional B3GalT4 Products

Product Documents for Human B3GalT4 (NP_003773) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Human B3GalT4 (NP_003773) VersaClone cDNA

For research use only

Related Research Areas

Glycobiology-related Enzymes

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